Correlation between serum myeloperoxidase with the severity of heart failure in children

Heart failure in children is a global major health problem. Inflammation an important role pathophysiology of heart failure. Myeloperoxidase (MPO) included to the inflammation cascade. The objective was analyze correlation between MPO with severity children. Observational analytic cross sectional study conducted on aged 1 month-18 years acyanotic CHD or without at Dr. Soetomo General Hospital Surabaya. Bivariate analysis used Mann Whitney test. Multivariate Kruskal Wallis. Correlation test Spearman’s significance value p<0.05. A total 21 subjects, median age 93 months old. most common type VSD. Moderate 28% 48% subjects were mild Median serum levels 36.25 (7.3-390) pg/ml. There no differences level distinguished by (p=0.62). (p=0.89). We concluded